Abstract No. 159 Effect of bleeding disorders on postoperative outcomes following lower extremity endovascular intervention for peripheral vascular disease

Conditions which interfere with coagulation may increase the risk of post-procedural bleeding and/or complications during interventional radiology procedures. This study investigates influence disorders on acute post-operative outcomes following lower extremity endovascular interventions for peripheral arterial disease (PAD). The 2014 to 2017 American College Surgeon’s National Surgical Quality Improvement Program database was filtered using CPT and ICD diagnosis codes relevant vascular interventions. Patients were divided into cohorts based a pre-operative disorder, including vitamin K deficiency, hemophilia, thrombocytopenia, or chronic anticoagulation that not discontinued prior procedure. Statistical analysis performed Fisher’s exact test assess differences in 30-day outcomes. A total 8022 patients included study, 5356 (67%) without disorder 2666 (33%) preprocedural disorder. at significantly increased mortality (odds ratio [OR] = 1.80, confidence interval [CI] 1.27-2.53, P 0.001), renal (OR 2.55, CI 1.48-4.38, 0.0001), cardiac 1.5, 1.01-2.07, 0.014), transfusion 1.96, 1.67-2.29, < 0.0001). In setting PAD, mortality, complications, transfusions compared disorders.